WELLNESS IMMUNE TEST

Biomarker Deep Dive

Magnesium (serum)

Magnesium is an abundant mineral which the body needs for many functions, including energy production, nerve function and muscle contraction. As the body can’t make it, we must acquire magnesium through the diet where it is absorbed via the small intestine. Approximately 50% of the body’s total magnesium is joined to calcium and phosphorus to make bone.

Why take a Magnesium blood test?
A magnesium blood test measures the amount of magnesium present in the blood. There is usually only a small amount, around 1%, of the body’s total magnesium in the blood. Magnesium levels may fluctuate if you have a condition affecting your kidney or intestine function. Magnesium levels can interfere with calcium level regulation and low magnesium levels can make it harder for low calcium levels to increase.
You can test your magnesium levels by purchasing a simple at-home finger prick test kit which is then analysed at an accredited lab. Forth offers a number of blood tests which include magnesium such as our Nutri-check test and Menopause Health blood test. A magnesium blood test is also available in some of our bigger blood test profiles such as Vitality which tests over 30 biomarkers integral to good health.

What function does Magnesium have in the body?
Magnesium is a co-factor in over 300 biochemical reactions including protein synthesis, muscle and nerve transmission and blood pressure regulation. So, it is important we acquire enough magnesium in our diet to fulfil the needs of the body. Magnesium is also vital for the structural function of proteins, mitochondria and nucleic acids.
Magnesium stabilises many enzymes, particularly those involved in energy production. Energy is essential for many of the body’s functions such as muscle contraction, production of fats, proteins and nucleic acids. For example, during muscle contraction magnesium is involved in the reuptake of calcium allowing contraction to take place. Magnesium also has an important role in bone mineralisation.

How do changes in Magnesium affect health and Wellbeing?
Magnesium has many functions within the body and so fluctuations in the levels of the mineral can affect our health and wellbeing. For example, low magnesium (hypomagnesemia) is associated with neurological issues like migraines, depression and epilepsy. It is uncommon for magnesium deficiency to occur in otherwise healthy individuals because the kidneys regulate its excretion. However, there are certain health conditions which can cause excessive magnesium losses or cause habitually low intakes such as chronic alcoholism and taking certain medications.

If your magnesium intake is routinely low, then this can cause changes in biochemical pathways, increasing the risk of illnesses, such as: high blood pressure, cardiovascular disease, type ii diabetes, osteoporosis, migraine headaches.

Equally, too much magnesium (hypermagnesemia) can make you feel quite unwell, inducing symptoms such as diarrhoea, abdominal cramping and nausea. Diarrhoea and the laxative effect of magnesium are caused by the osmotic activity in the intestine by unabsorbed salts and the promotion of gastric motility.

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